Circulating Extracellular Vesicles Contain Liver-Derived RNA Species as Indicators of Severe Cholestasis-Induced Early Liver Fibrosis in Mice
Sharmila Fagoonee 1, Maddalena Arigoni 2, Marta Manco 2, Martina Olivero 3, Francesca Bizzaro 4, Cinzia Magagnotti 5, Annapaola Andolfo 5, Barbara Miniscalco 6, Marco Forni 2, Stefano Todeschi 4, Emanuela Tolosano 2, Elena Bocchietto 4, Raffaele Calogero 2, Fiorella Altruda 2
1Department of Biological Sciences, Institute of Biostructure and Bioimaging, National Research Council, Molecular Biotechnology Center, Turin, Italy
2Department of Molecular Biotechnology and Health Sciences, Molecular Biotechnology Center, University of Turin, Turin, Italy
3Department of Oncology, University of Turin, Torino, Italy
4Abich S.r.l., Biological and Chemical Analysis, Verbania, Italy
5ProMeFa, Proteomics and Metabolomics Facility, IRCCS, San Raffaele Scientific Institute, Milan, Italy
6Department of Veterinary Sciences, University of Turin, Italy
Endocrine Disruption by Mixtures in Topical Consumer Products
Emiliano Ripamonti1, Elena Allifranchini1, Elena Bocchietto1, Stefano Todeschi1
1Abich srl, biological and chemical toxicology research laboratory, Verbania (VB), Italy
SUNSCREEN TESTING: ethics, limits and critical points
Elena Bocchietto1, Stefano Todeschi2
1Director of the testing facility Abich srl, biological and chemical toxicology research laboratory, Verbania (VB), Italy and 2CEO Abich srl, biological and chemical toxicology research laboratory, Verbania (VB), Italy
Behind the Claim. Skin moisturizing: how to choose the best assay
Elena Bocchietto1, Stefano Todeschi2
1Director of the testing facility Abich srl, biological and chemical toxicology research laboratory, Verbania (VB), Italy and 2CEO Abich srl, biological and chemical toxicology research laboratory, Verbania (VB), Italy
Behind the Claim: dermatologically tested, hypoallergenic or clinically tested?
Elena Bocchietto1, Stefano Todeschi2
1Director of the testing facility Abich srl, biological and chemical toxicology research laboratory, Verbania (VB), Italy and 2CEO Abich srl, biological and chemical toxicology research laboratory, Verbania (VB), Italy
Cytotoxicity evaluation of electronic cigarette vapor extract on cultured mammalian fibroblasts (ClearStream-LIFE): comparison with tobacco cigarette smoke extract
Giorgio Romagna1, Elena Allifranchini1, Elena Bocchietto1, Stefano Todeschi1, Mara Esposito1, and Konstantinos E. Farsalinos2
1Abich srl, biological and chemical toxicology research laboratory, Verbania (VB), Italy and 2Department of Cardiology, Onassis Cardiac Surgery Cente, Kallithea, Greece
Comparison of the Cytotoxic Potential of Cigarette Smoke and Electronic Cigarette Vapour Extract on Cultured Myocardial Cells
Konstantinos E. Farsalinos 1,*, Giorgio Romagna 2, Elena Allifranchini 2, Emiliano Ripamonti 2, Elena Bocchietto 2, Stefano Todeschi 2, Dimitris Tsiapras 1, Stamatis Kyrzopoulos 1 and Vassilis Voudris 1
1 Onassis Cardiac Surgery Center, Sygrou 356, Kallithea 17674, Greece;
2 ABICH S.r.l, Biological and Chemical Toxicology Research Laboratory, Via 42 Martiri,213/B-28924 Verbania (VB), Italy
Limiti di HRIPT e metodi alternativi
Samuele Burastero1 e Stefano Todeschi2
1Laboratorio immunologia e allergologia molecolare, San Raffaele Scientific Institute – Milano 2Laboratori Abich – Verbania
Decontamination of tetramethylammonium hydroxide (TMAH) splashes: promising results with Diphoterine® in vitro
Céline Fosse1, Laurence Mathieu1, Alan H. Hall2,3, Elena Bocchietto4, François Burgher1, Michel Fischbach4, and Howard I. Maibach5
1Laboratoire Prevor, Valmondois, France, 2Toxicology Consulting and Medical Translating Services, Inc. (TCMTS, Inc.), Laramie, Wyoming, USA, 3Colorado School of Public Health, Denver, Colorado, USA, 4ABICH Srl, Verbano, Italy, and 5Department of Dermatology, University of California–San Francisco, San Francisco, California, USA
HUMAN MONOCYTOID THP-1 CELL LINE VERSUS MONOCYTE-DERIVED HUMAN IMMATURE DENDRITIC CELLS AS IN VITRO MODELS FOR PREDICTING THE SENSITISING POTENTIAL OF CHEMICALS
E. BOCCHIETTO, C. PAOLUCCI1, D. BREDA1, E. SABBIONI2 and S.E. BURASTERO1
Abich, Tecnoparco, Lago Maggiore, Verbania; 1San Raffaele Scientific Institute, Department of Biotechnology, Milan; 2European Centre for the Validation of Alternative Methods, Joint Research Centre, Ispra, Varese, Italy