Detangling combing test
| Regulatory reference: | Proprietary method |
| Claim: | Improves combing |
| Application field: | Hair products. |
| Description of the test: | Dynamometric analysis of the resistance to combing on standardized hair locks. Comparison between treated and untreated wet locks. Results in terms of combing friction (in Newtons) and percentage of friction reduction compared to the untreated control. |
Posted in Improves combing, Hair products, Claim for cosmetics
Hair resistance to breakage assay
| Regulatory reference: | Proprietary method |
| Claim: | Strenghtener |
| Application field: | Strengthening hair products. |
| Description of the test: | Dynamometric analysis of the tensile strength and resistance to breakage on treated and untreated hairs collected ex vivo from 20 volunteer. Results in terms of tensile strength (in Newtons) and percentage of strengthening compared to the untreated control. |
Posted in Strenghtener, Hair products, Claim for cosmetics
Analysis of the protection granted by sunscreens in the high energy visible spectrum (HEV/blue light 400-500 nm)
| Regulatory reference: | Proprietary method based on ISO 24443 |
| Claim: | Protects against the high energy visible (HEV) spectrum or Blue light protection |
| Application field: | Suncreen products. |
| Description of the test: | Analysis of the absorbance spectrum of a sunscreen product in the HEV spectrum versus blank. Results in terms of absorbance curve and percentage of light blocked in the 400-500 nm specturm. |
5α-reductase inhibition efficacy test by mRNA analysis on dermal papillae cells
| Regulatory reference: | Proprietary method |
| Claim: | Seboregulating |
| Application field: | Active ingredients or finished products. |
| Description of the test: | Quantification of the changes in the gene expression of 5α-reductase in human dermal papilla cells. Demonstration of the efficacy of the ingredient or finished product in reducing the expression of mRNA codifying for 5α-reductase type I or II. |
Posted in Acne, Seboregulating, Claim for cosmetics
5α-reductase inhibition efficacy test by mRNA analysis
| Regulatory reference: | Proprietary method |
| Claim: | Seboregulating and Hair loss protection |
| Application field: | Active ingredients or finished products. |
| Description of the test: | Quantification of the changes in the gene expression of 5α-reductase in murine Balb/3T3 fibroblasts. Demonstration of the efficacy of the ingredient or finished product in reducing the expression of mRNA codifying for 5α-reductase type I or II. |
Posted in Acne, Seboregulating, Hair loss protection, Hair products, Claim for cosmetics
5α-reductase inhibition efficacy test
| Regulatory reference: | Proprietary method |
| Claim: | Seboregulating and Hair loss protection |
| Application field: | Active ingredients or finished products. |
| Description of the test: | Analysis of the in vitro expression of the 5α-reductase enzyme by real time PCR in comparison with untreated substrates for the evaluation of inhibition effects. Demonstration of the efficacy of the ingredient or finished product in reducing the expression of mRNA codifying for 5α-reductase type I or II. |
Posted in Acne, Seboregulating, Hair loss protection, Hair products, Claim for cosmetics
Evaluation of the efficacy in the modulation of melanogenesis in pigmented cells by quantification of the expression of the tyrosinase gene
| Regulatory reference: | Proprietary method |
| Claim: | Skin whitening and Depigmenting action |
| Application field: | Active ingredients or finished products. |
| Description of the test: | Evaluation of the changes in the expression of the tyrosinase gene in human melanoma cells. |
Evaluation of the efficacy in the modulation of melanogenesis in pigmented cells
| Regulatory reference: | Proprietary method |
| Claim: | Tanner |
| Application field: | Active ingredients or finished products. |
| Description of the test: | Quantification of the increase of melanin synthesis in human melanoma cells treated with the sample substance or product in comparison with untreated controls. The same test can be used to quantify a reduction in melanin synthesis. |
Lipase stimulation efficacy test
| Regulatory reference: | Proprietary method |
| Claim: | Anti-cellulite and Seboregulating |
| Application field: | Active ingredients or finished products. |
| Description of the test: | Analysis of the activation of the activity of enzymatic lipase in a controlled triglyceride hydrolysis reaction. |
Posted in Acne, Anti-cellulite, Seboregulating, Cellulite, Claim for cosmetics
Evaluation of lipolysis efficacy on pre-adipocytes
| Regulatory reference: | Proprietary method |
| Claim: | Anti-cellulite |
| Application field: | Active ingredients or finished products. |
| Description of the test: | Evaluation of the reduction of intracellular lipid accumulation in adipocyte cells treated with several concentrations of the tested product, in comparison to untreated adipocytes. |
Posted in Anti-cellulite, Cellulite, Claim for cosmetics
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