Regulatory reference: | Proprietary method |
Claim: | Hydrates the skin |
Application field: | Complete products. |
Description of the test: | Analysis of the expression of aquaporing through real time PCR. |
Regulatory reference: | Proprietary method based on ISO 24443:2012 |
Claim: | Water resistant |
Application field: | Sunscreen creams, sticks and cosmetic products. |
Description of the test: | Determination of the percentage of water resistance of a sunscreen product on PMMA plates with measurements before and after washes in controlled conditions. The preliminary test requires confirmation through in vivo tests. |
Regulatory reference: | ISO 16217/18861 |
Claim: | Water resistant or Very water resistant |
Application field: | Sunscreen creams, sticks and cosmetic products. |
Description of the test: | Determination of the percentage of persistence of the Sun Protection Factor (SPF) on healthy volunteers after washing in controlled conditions. |
Regulatory reference: | OECD n° 491 |
Claim: | Non-irritant for the eyes (CLP Labeling) |
Application field: | Raw ingredients or finished products. |
Description of the test: | Short term exposure analysis by application of each tested substance on SIRC (Statens Seruminstitut Rabbit Cornea) cells for the determination of the effect on cell viability through MTT test. |
Regulatory reference: | OECD n° 439 |
Claim: | Non-irritant for the skin |
Application field: | Chemical substances or mixtures. |
Description of the test: | Patch test for the evaluation of the irritation potential of chemical substances or mixtures through evaluation of their cytotoxic effect on an in vitro reconstructed model of human skin. |
Regulatory reference: | ISO 24443:2012 |
Claim: | Broad spectrum protection |
Application field: | Sunscreen creams, sticks and cosmetic products. |
Description of the test: | Determination of the UVA protection and critical wavelength according to the ISO guideline for broad spectrum protection testing. |
Regulatory reference: | Proprietary method |
Claim: | Skin whitening and Depigmenting action |
Application field: | Active ingredients or finished products. |
Description of the test: | Quantification of the inhibition of melanin synthesis in human melanoma cells exposed to the substance or product to be tested, in comparison with untreated controls. The same test can also be used to quantify an increase of melanin synthesis. |
Regulatory reference: | Proprietary method |
Claim: | Control of the aggregational state of physical filters |
Application field: | Sunscreen creams, sticks and cosmetic products. |
Description of the test: | Microscopical analysis and high resolution imaging of the aggregation of physical filters. Includes measurement of the size of aggregates, if present. |
Regulatory reference: | Proprietary method |
Claim: | Anti-dandruff |
Application field: | Anti-dandruff hair products, ingredients or finished products. |
Description of the test: | Evaluation of the anti-dandruff efficacy by testing the inhibition of the proliferation of Malassezia furfur by an ingredient or finished product. |