Depigmenting action

Evaluation of the enzymatic inhibition of Tyrosinase

Regulatory reference:	Proprietary method
Claim:	Depigmenting action
Application field:	Active ingredients, mixtures or finished products.
Description of the test:	Evaluation of the efficacy of a sample in inhibiting the activity of the tyrosinase enzyme in a controlled in vitro direct reaction.

Posted in Blemish reduction, depigmenting, tanning, Depigmenting action, Claim for cosmetics

Evaluation of the modulation of melanogenesis on pigmented cells

Regulatory reference:	Proprietary method
Claim:	Skin whitening and Depigmenting action
Application field:	Active ingredients or finished products.
Description of the test:	Quantification of the inhibition of melanin synthesis in human melanoma cells exposed to the substance or product to be tested, in comparison with untreated controls. The same test can also be used to quantify an increase of melanin synthesis.

Posted in Skin whitening, Blemish reduction, depigmenting, tanning, Depigmenting action, Claim for cosmetics

Evaluation of the efficacy in the modulation of melanogenesis in pigmented cells by quantification of the expression of the tyrosinase gene

Regulatory reference:	Proprietary method
Claim:	Skin whitening and Depigmenting action
Application field:	Active ingredients or finished products.
Description of the test:	Evaluation of the changes in the expression of the tyrosinase gene in human melanoma cells.

Posted in Skin whitening, Blemish reduction, depigmenting, tanning, Depigmenting action, Claim for cosmetics